1 in 10 Has an Elevated PSA – Here Are 5 Causes

1 in 10 Has an Elevated PSA – Here Are 5 Causes

Every year, over 10,000 men in Sweden are diagnosed with prostate cancer, and more than 115,000 are living with the disease. Prostate cancer is most common in men over 60, but those with a family history of the disease may consider testing their PSA levels at a younger age to detect any abnormalities early.

Quick version

Through a simple blood test, the concentration of PSA (prostate-specific antigen) can be measured, providing an early indication of changes in the prostate. Elevated PSA levels occur in about 1 in 10 men and can be caused by several factors; it does not always indicate cancer. Elevated levels may also be due to benign prostate enlargement or inflammation but may still require further investigation to ensure prostate health.

5 Causes of Elevated PSA

  • Prostate Cancer
    One of the most serious causes of elevated PSA, where early detection can improve the chances of effective treatment.

  • Benign Prostatic Hyperplasia (BPH)
    A common, non-cancerous enlargement of the prostate that often causes elevated PSA levels, particularly in older men.

  • Prostatitis (Inflammation of the Prostate)
    An infection or inflammation that can lead to temporarily elevated PSA levels, often with symptoms such as pain and discomfort during urination.

  • Prostate Trauma
    Injury or pressure on the prostate, such as after certain medical procedures or intense cycling, can cause a temporary increase in PSA levels.

  • Age
    PSA levels naturally increase with age, meaning older men often have higher PSA without necessarily indicating disease.

Why Early Detection of Elevated PSA Levels Is Important

PSA is a protein produced by the prostate gland and is naturally found in the blood. Elevated PSA levels can gradually occur with prostate cancer but also with other conditions like benign prostatic hyperplasia (BPH) or inflammation in the prostate (prostatitis). While elevated PSA may not be caused by cancer, it is still important to detect and monitor changes, especially when combined with other risk factors or symptoms.

Early indications of changes in the prostate allow for quicker intervention and increase the chances of effective treatment, regardless of the underlying cause. Regular PSA monitoring can therefore help detect problems before they develop into more serious conditions, which can be crucial for long-term health and quality of life.

Risk of Overdiagnosis and the Importance of Professional Interpretation

While an elevated PSA can provide valuable information about prostate health, there is also a risk of overdiagnosis. PSA levels can increase for several reasons without indicating a serious illness like prostate cancer. Therefore, it is important not to interpret PSA results in isolation. An elevated PSA result should be followed up and evaluated by a physician who considers the patient's overall health, lifestyle, and any risk factors. A professional assessment helps determine if further testing is needed and reduces the risk of unnecessary concern and treatment for changes that do not require immediate intervention.

How Is a PSA Test Done?

A PSA test is simple and performed through a blood sample taken at a healthcare center or clinic. No extensive preparation is required, but it is recommended to avoid intensive physical activity, such as cycling, for at least 48 hours before the test to prevent influencing the results. Results are usually available within a few days and can help the physician assess whether further investigation is needed.

What Happens If the PSA Test Shows High Levels?

If your PSA level is elevated, the first step is for your doctor to assess whether further tests are necessary. An elevated PSA level does not automatically mean cancer, and the doctor may want to repeat the test or perform other examinations, such as an MRI scan or biopsy, to gain a clearer understanding. Regardless of the results, regular follow-up is often part of the care plan to detect any changes early over time.

At What Age Should a PSA Test Be Considered?

For most men, it is recommended to start considering PSA testing at age 50. Men at higher risk, such as those with close relatives who have had prostate cancer, may consider testing as early as 45. Discussing when and how often to test with your physician is important to balance the benefits and potential risks of regular PSA screening.

Regular Monitoring

By regularly monitoring your PSA levels, you increase your chances of detecting potential problems early. A PSA test can monitor not only cancer but also other conditions like benign prostatic hyperplasia and prostatitis. Tracking PSA levels over time allows for early detection of changes that may require further attention before they develop into more significant health issues.

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