What is arsenic?
P-Arsenic is a biomarker that measures arsenic levels in the blood and is used to assess arsenic exposure. Arsenic occurs naturally in soil, water, and air and is particularly dangerous in its inorganic form, which can cause serious health problems with long-term exposure. The main sources of inorganic arsenic are contaminated drinking water and rice, which readily absorbs arsenic from the soil. Prolonged exposure increases the risk of cancer, cardiovascular diseases, and nerve damage, with children and fetuses being particularly sensitive to these effects.
Why is p-Arsenic important to analyze?
Analyzing the concentration of arsenic in the blood is essential to assess a person's arsenic exposure. Long-term exposure to high concentrations of arsenic has been linked by the World Health Organization (WHO) to serious health risks, such as cancer, skin diseases, and damage to the cardiovascular and nervous systems. Monitoring arsenic levels is especially important in areas where groundwater contains high levels of inorganic arsenic, as this form of arsenic is toxic and poses a significant health risk over time.
What can cause elevated arsenic levels?
High concentrations of arsenic in the body can be caused by several different factors, often related to external factors such as environment and diet. Below are some common causes of elevated arsenic levels:
- Contaminated drinking water: In some regions, groundwater may be contaminated with higher levels of arsenic, leading to higher concentrations with prolonged exposure.
- Contaminated food: Certain foods, especially rice and seafood, may contain high levels of arsenic depending on where they are grown or harvested.
- Industrial pollution: Arsenic is used in some industrial processes, and people who work in or live near these industries may be at higher risk.
- Smoking: Tobacco contains small amounts of arsenic, and long-term smoking can increase exposure.
Reference range for arsenic, As (B-)
In a blood test, the reference range for arsenic (B-As) is typically between 0.01–0.05 µmol/L in individuals without known exposure to high levels of arsenic. This corresponds to normal levels in the blood under typical conditions. Important! Note that reference ranges may vary depending on the analysis method and laboratory.
Levels above this range can indicate increased exposure, especially at values over 0.67 µmol/L (equivalent to 50 µg/L), which is considered a threshold where poisoning or chronic exposure should be further investigated. Such levels may result from exposure to inorganic arsenic through contaminated drinking water, work environments, or food sources.
If arsenic exposure is suspected, it is recommended to take steps to reduce exposure and monitor arsenic levels through follow-up blood tests.
Practical advice for managing arsenic exposure
- Test your water: If you live in an area with known arsenic risks, regularly test your drinking water. Use certified laboratories for accurate results.
- Use water filters: Invest in a water filter that effectively reduces arsenic levels in your drinking water. Ensure the filter is certified to remove inorganic arsenic.
- Be mindful of your diet: Certain foods, especially rice and seafood, may contain higher levels of arsenic. Limit the intake of these foods or choose varieties with lower arsenic content.
- Regular health check-ups: If you suspect you have been exposed to high levels of arsenic, consult a doctor for a comprehensive health check, including a blood test for P-Arsenic.