Dihydrotestosterone (DHT) - Analysis of DHT Levels in the Blood
This test measures the levels of dihydrotestosterone (DHT) in the body, an important hormone that plays a central role in the development of male sexual characteristics, hair growth, and prostate function. DHT is formed from testosterone via the enzyme 5-alpha-reductase and is a highly potent androgen, particularly active in the skin, hair follicles, and prostate. This analysis is particularly useful for identifying hormonal imbalances that may cause hair loss, benign prostatic hyperplasia (BPH), or other androgen-related conditions.
Uses of the DHT Test
The DHT test is used in various clinical situations where it is important to assess androgen levels and their impact on different bodily functions. Common conditions or investigations where the test is recommended include:
- Suspected hair loss (androgenetic alopecia) to assess whether hair loss is caused by elevated DHT levels.
- Investigation and monitoring of benign prostatic hyperplasia (BPH) to evaluate treatment effectiveness or monitor disease progression.
- Puberty abnormalities in boys such as delayed or early puberty, where DHT plays a crucial role in the development of sexual characteristics.
- Follow-up of hormonal treatments particularly in cases of gender dysphoria or hormonal therapies affecting androgen production.
When is a DHT Test Recommended?
DHT analysis is recommended in cases of suspected androgen-related conditions such as hair loss, prostatic hyperplasia, or hormonal imbalances. The test is also relevant for monitoring the effects of hormonal treatments that affect DHT production. The test is performed through venous blood sampling and provides reliable results for detecting abnormalities in DHT levels that may impact the patient's health.
Reference Range for DHT
Normal reference values for DHT are typically between 0.4 - 2.5 µg/L in adult men. Elevated DHT levels may indicate conditions such as androgenetic alopecia or benign prostatic hyperplasia, while low DHT levels may signal androgen deficiency, which can affect sexual function or pubertal development. Reference values may vary depending on the laboratory's analysis methods.
