S-ACE

595 kr
ACE

Angiotensin converting enzyme

S-ACE

595 kr
  • Analysis of S-ACE (Serum Angiotensin Converting Enzyme).
  • Blood test in the investigation of sarcoidosis and granulomatous diseases.
  • Elevated levels may indicate active sarcoidosis or other inflammatory conditions.
  • Used to assess disease activity and response to treatment.
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Information about S-ACE

S-ACE (Serum Angiotensin Converting Enzyme) is an enzyme that plays a central role in the body's renin-angiotensin system, where it converts angiotensin I to the biologically active form angiotensin II. This is crucial for blood pressure regulation and fluid balance. Elevated levels of S-ACE are primarily seen in sarcoidosis, an inflammatory disease in which granuloma formation in the lungs and other organs can increase the production of ACE. Therefore, the analysis is often used as a supporting biomarker in the diagnosis and follow-up of sarcoidosis.

S-ACE is produced in several tissues, including the lungs, kidneys and vascular endothelium, but the level in the blood can be affected by inflammatory diseases and certain drugs. Elevated S-ACE values ​​can be seen in other granulomatous diseases as well as in certain metabolic and autoimmune conditions.

Why is S-ACE analysis performed?

A blood test for S-ACE is primarily used to:

  • Investigate and monitor sarcoidosis, especially in cases of lung involvement.
  • Differentiate sarcoidosis from other granulomatous diseases, such as tuberculosis and berylliosis.
  • Assess disease activity and response to treatment in patients with sarcoidosis.
  • Evaluate certain hypertension and kidney diseases, where the renin-angiotensin system may be affected.

When might an analysis of S-ACE be relevant?

The blood test for S-ACE is used in healthcare to evaluate inflammatory diseases, primarily sarcoidosis. It may be relevant for:

  • Suspected sarcoidosis – with symptoms such as persistent cough, shortness of breath, fatigue and lymph node enlargement.
  • Treatment follow-up – S-ACE can be used to monitor the effect of corticosteroid treatment in sarcoidosis.
  • Investigation of granulomatous diseases – for example tuberculosis and berylliosis.
  • Assessment of renal involvement – ​​with suspicion of the renin-angiotensin system’s influence on blood pressure and fluid balance.

Interpretation of S-ACE test results

  • Normal levels: Indicates the absence of active granulomatous inflammation.
  • Elevated levels: Often seen in active sarcoidosis but can also occur in other granulomatous or inflammatory diseases.
  • Low levels: May be caused by treatment with ACE inhibitors or kidney-related factors affecting enzyme activity.

It is important to note that S-ACE is not a specific marker for sarcoidosis and should always be interpreted in combination with other diagnostic methods, such as chest X-ray, serum calcium and inflammation parameters.

Reference range for S-ACE

Reference values ​​for S-ACE vary between laboratories, but a common upper reference limit is:

  • 8–52 U/L for adults

Elevated S-ACE values ​​should always be evaluated by the treating physician in conjunction with other clinical findings.

ACE
S-ACE
S-ACE (Serum Angiotensin Converting Enzyme) is a biomarker used in the investigation of sarcoidosis and blood pressure regulation. Elevated levels may indicate granulomatous diseases, while low values ​​are seen with ACE inhibitor therapy.
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Before visiting a reception for sampling, you need to do the following:

Activate referral and select reception

To activate your referral, simply follow the instructions that you will receive via email after completing the purchase. The email contains an activation code, by clicking on the link in the email you enter the flow to fill in any information, activate the referral and select reception in the sample answer service zample.

Before the sampling

  • Rest for 15 minutes in place on the sampling unit.
  • Bring valid identification.

The referral is available digitally at the sampling unit after you activate it, follow the instructions you receive via email. Here you can read our guidelines before taking samples.

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Add the health check or tests you want to carry out to the shopping cart, go to checkout and choose the payment option that suits you. After completed payment, we will send an email with an activation code for your referral. You use the activation code in the sample response service "My journal" to activate the referral and select the reception where you want to leave your samples.

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